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Updated: May 25, 2025

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
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A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

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聚合体介导的Cbl-b沉默激活T细胞对抗固体瘤

Guanhong Cui1, Yu Shao2, Junyao Wang2

  • 1Biomedical Polymers Laboratory, College of Chemistry, Chemical Engineering and Materials Science, and State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, 215123, P. R. China. xucc@suda.edu.cn.

Biomaterials science
|February 28, 2025
PubMed
概括

在T细胞中沉默卡西塔斯B系淋巴瘤原瘤基因b (Cbl-b) 增强了抗瘤免疫力. 这种新的策略使用聚合体来输送siRNA,增强T细胞功能并抑制癌症免疫疗法的瘤进展.

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