在一项多中心随机对照试验中招募问题,该试验涉及文化配方访谈对治疗工作联盟的影响
Alma M Brand1, Simon P N Groen2, Samrad Ghane3
1Tilburg Universiteit, Tilburg, Netherlands.
Contemporary clinical trials communications
|February 28, 2025
概括
在多中心随机对照试验中招募挑战是常见的. 分享这些经验有助于研究人员改善参与者招聘和资源管理.
科学领域:
- 临床试验 临床试验
- 医疗保健服务研究 医疗服务研究
- 研究方法研究方法研究方法学
背景情况:
- 多中心随机对照试验 (RCT) 对于医学知识的进步至关重要.
- 在进行大规模临床试验时,有效的参与者招募是一个重大挑战.
- 之前的研究突出了招聘的各种障碍,需要对实际策略进行持续审查.
研究的目的:
- 详细说明在特定多中心随机对照试验中遇到的预期和意想不到的招聘问题.
- 为管理类似试验的研究人员提供实际见解和建议.
- 优化资源配置和参与者参与临床研究.
主要方法:
- 本文回顾了多中心随机对照试验的招聘流程和挑战.
- 它确定了在试验的不同组织层面出现的问题.
- 经验被记录下来,以告知未来的试验设计和执行.
主要成果:
- 预期的招聘挑战包括[具体的例子,如果有].
- 出现了一些意想不到的问题,如[具体的例子,如果可用],影响了入学时间表.
- 现场和中央层面的组织因素影响了招聘成功.
结论:
- 积极的规划和适应性策略对于克服多中心RCT招聘障碍至关重要.
- 分享实践经验有助于完善招聘协议,提高研究效率.
- 解决招聘问题有效地确保了试验数据的完整性,并尊重参与者的贡献.
相关概念视频
Elements Crucial for Effective Psychotherapy
29
Research has highlighted several critical factors that influence the effectiveness of psychotherapy, such as the therapeutic alliance, the therapist, and the client.
The Therapeutic Alliance
The therapeutic alliance refers to the relationship between the therapist and the client. The alliance strengthens when the therapist and the client engage in a nurturing, supportive, trusting, empathetic, and respectful relationship, improving therapeutic outcomes. Therapists must monitor this relationship...
The Therapeutic Alliance
The therapeutic alliance refers to the relationship between the therapist and the client. The alliance strengthens when the therapist and the client engage in a nurturing, supportive, trusting, empathetic, and respectful relationship, improving therapeutic outcomes. Therapists must monitor this relationship...
29
Psychological and Sociocultural Causes of Schizophrenia
43
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
43
Group Therapy
21
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
21
Robbers Cave
14.2K
During the 1950s, the landmark Robbers Cave experiment demonstrated that when groups must compete with one another, intergroup conflict, hostility, and even violence may result. At the Oklahoman summer camp, two troops of boys—termed the Rattlers and the Eagles—took part in a week-long tournament. During this time, their negativity culminated in derogatory name-calling, fistfights, and even vandalism and destruction of property. However, this work also revealed that such tension...
14.2K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
111
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
111
Surveys
14.7K
Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
14.7K


