使

Pavel Kohout1,2, Michal Vasina1,2, Marika Majerova1,2

  • 1Loschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Brno 611 37, Czech Republic.

JACS Au
|February 28, 2025
PubMed
概括

一种新的机器学习方法通过提高蛋白质溶解性和稳定性来增强酶设计. 这种方法,使用变异自编码器,成功设计了具有较高稳定性和活性的类脱酶,用于工业应用.

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