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Updated: May 25, 2025

Spatial and Temporal Control of T Cell Activation Using a Photoactivatable Agonist
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记忆CD4+T细胞在逐步激活过程中顺序重组它们的3D基因组

Alexander I Ward1, Jose I de Las Heras2, Eric C Schirmer2

  • 1Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, London, United Kingdom.

Frontiers in cell and developmental biology
|February 28, 2025
PubMed
概括

记忆CD4+T细胞在对刺激的反应中表现出动态的3D染色体结构变化. 这些结构性转变是由细胞因子和共受体驱动的,这些细胞是基因表达反应的主要细胞.

关键词:
三维基因组组织3D基因组组织这就是Hi-C.在IL-2中,IL-2被认为是IL-2.增强者 促进者 互动.调节基因表达 调节基因表达记忆 CD4+ T 细胞原始化/脱原始化的基因.顺序性免疫激活系统

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