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Updated: May 25, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
06:50

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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CFAP410具有双模块架构,其N端氨酸丰富的重复图案上有一个保留的表面补丁,用于绑定相互作用伙伴

Alexander Stadler1,2, Heloisa B Gabriel3, Laryssa V De Liz3

  • 1Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.

Frontiers in cell and developmental biology
|February 28, 2025
PubMed
概括

纤毛和鞭毛相关蛋白410 (CFAP410) 突变通过破坏其结构而导致疾病. 这项研究揭示了N端域结构,解释了突变如何破坏蛋白质相互作用并导致纤毛发育障碍.

关键词:
在CFAP41010中使用.纤维病变 (ciliopathy) 是一种纤维病变.片 (cilium cilium) 是一种类型的细胞.旗的小部分是flagellum蛋白质蛋白质是蛋白质蛋白质的组成部分.结构 结构 结构 结构

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