评估术后局部抗生素在白内障手术中的疗效:系统性审查和元分析
Maria Laura Passaro1,2, Matteo Posarelli3,4, Fabio Claudio Avolio1
1Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples 'Federico II', Naples, Italy.
Acta ophthalmologica
|February 28, 2025
概括
仅靠室内抗生素就足以预防白内障手术后的内炎. 手术后添加局部抗生素在减少感染率方面没有显著的益处,可能会降低抗菌素耐药性.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 外科手术的结果
背景情况:
- 白内障手术是全球最常见的手术,其中内炎具有显著的风险.
- 内腔 (IC) 抗生素是预防术后感染的标准.
- 需要额外的手术后局部抗生素仍然是有争议的.
研究的目的:
- 系统地审查和分析局部抗生素在预防内的疗效.
- 为了比较在接受IC抗生素与或没有术后局部抗生素的患者的结果.
主要方法:
- 31项研究的系统审查和元分析.
- 包括超过120万个眼睛接受了发光乳化白内障手术.
- 单独的室内抗生素与室内加上局部抗生素之间的比较.
主要成果:
- 两组之间内眼炎发病率没有统计学上显著的差异 (p=0.97).
- 这两组都表现出0.0004 (95%CI:0.0003-0.0005) 的低发病率.
- 手术后的局部抗生素没有提供额外的保护性益处.
结论:
- 单独使用室内抗生素可能足以预防.
- 术后常规使用局部抗生素可能是不必要的.
- 减少局部抗生素的使用可能有助于打击抗菌素耐药性.
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