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Updated: May 24, 2025

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在非编码区域中识别精神分裂风险调节变异rs1399178及其对NRF1结合的影响

Lei Ji1,2,3, Bojian Huang1,2,3, Decheng Ren1,2,3

  • 1Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai Jiao Tong University, Shanghai, China.

CNS neuroscience & therapeutics
|February 28, 2025
PubMed
概括

一种精神分裂症风险变体rs1399178改变了核呼吸因子1 (NRF1) 的结合和功能. 这种促进剂-增强剂切换机制为精神分裂症遗传学和潜在的治疗点提供了新的见解.

关键词:
这就是NRF1的NRF1.TF-具有约束力的法规.功能性基因组学 功能性基因组学需要使用 rs13991788.精神分裂症是一种精神分裂症.结构分析是结构分析.

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