血清可溶性内分泌物可能是早产预测器
Rekha Sachan1, Anamika Shahi1, Pushplata Sachan2
1Department of Obstetrics and Gynaecology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Annals of African medicine
|February 28, 2025
概括
血清内分泌水平可能有助于预测早产的结果. 在中度早产和24小时内分娩时观察到更高的水平,这表明其预后潜力.
科学领域:
- 生殖医学 生殖医学
- 生物化学 生物化学
背景情况:
- 过早分娩影响全球10%的分娩,对围产死亡率和发病率做出了重大贡献.
- 评估用于预测早产的新生物标志物至关重要.
研究的目的:
- 评估血清溶解的Endocan (ESM1) 水平,用于预测和预后早产.
- 调查血清Endocan水平与分娩时的妊娠年龄之间的相关性.
主要方法:
- 对124名已确立早产的孕妇进行前性观察性研究.
- 使用ELISA测量血清内多坎水平.
- 按妊娠年龄分类的女性:极端,非常,中度,晚期早产和满期分娩.
主要成果:
- 平均血清Endocan水平在中度过早分娩 (866.64 pg/ml) 和24小时内分娩 (839.52 pg/ml) 中最高.
- 与满期分娩相比,在非常早产和晚期早产组中也发现了较高的Endocan水平.
- 大多数参与者BMI正常,并且是初级妊娠.
结论:
- 血清Endocan显示出作为早产预后标志物的潜力.
- 早期检测和干预对于管理早产风险至关重要.
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