监测结肠镜定时对晚期腺瘤切除后结肠直肠癌发生率的影响
Munenori Honda1, Yasushi Oda2, Ryosuke Gushima1
1Department of Gastroenterology and Hepatology, Kumamoto University Hospital, Kumamoto, Japan.
The American journal of gastroenterology
|February 28, 2025
概括
在晚期腺瘤 (AA) 诊断后及时监测结肠镜显著降低了结肠直肠癌 (CRC) 风险. 对于AA患者来说,在3年内进行首次监测至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 预防医学 预防医学
背景情况:
- 索引结肠镜检查结果影响结肠直肠癌 (CRC) 监测策略.
- 监测结肠镜定时对CRC风险降低的影响尚未完全理解.
研究的目的:
- 评估第一次监视结肠镜检查的时间是否会影响CRC发病率.
- 根据发现,根据指标结肠镜检查后确定最佳监测间隔.
主要方法:
- 在2005年至2021年期间,对20397人进行了回顾性队列研究.
- 根据指标结肠镜检查结果分为四组:晚期腺瘤 (AA),≥3个非AA,1-2个非AA,没有腺瘤.
- 基于第一次监测间隔 (<或>3年) 的CRC累计发病率的比较.
主要成果:
- 在不同群体中发现了50例CRC病例.
- 第一次监测间隔>3年与AA组中较高的CRC发病率有关 (HR3.49,P=0.04).
- 对于其他群体,没有发现显著的关联.
结论:
- 3年内监测结肠镜与晚期腺瘤 (AA) 患者的CRC风险降低有关.
- 3年监测间隔对于AA的受试者特别有效.
- 这凸显了遵守推的监测间隔的重要性.
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