人体肠道微生物组的功能调节由奶酪传递的细菌进行
Christian Milani1,2, Giulia Longhi1, Giulia Alessandri1
1Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy.
Applied and environmental microbiology
|February 28, 2025
概括
微小的奶酪细菌,如Hafnia,可以改变人类肠道微生物群的组成和功能. 这些微生物引入有益的基因,扩大肠道.
科学领域:
- 微生物学 微生物学
- 人类健康 人类健康 人类健康
- 食品科学 食品科学 食品科学
背景情况:
- 奶酪是全球消费的发酵食品,对人类健康产生影响.
- 奶酪微生物群落对人类肠道微生物群的作用尚未完全理解.
研究的目的:
- 研究奶酪微生物如何调节人类肠道微生物群的分类学和功能潜力.
- 为了确定负责这些调制的特定奶酪相关细菌.
主要方法:
- 使用了体外人体肠道模拟培养模型.
- 采用多组学方法 (基因组学,转录组学,代谢组学).
- 在人体便样本中的痕迹奶酪细菌菌株.
主要成果:
- 奶酪中的小细菌参与者,包括菌,细菌,菌和哈夫尼亚,调节肠道微生物群.
- 这些细菌引入了扩大肠道功能潜力的基因 (例如,维生素,氨基酸合成).
- 观察到从奶酪细菌向人类肠道微生物群的水平基因转移的证据.
结论:
- 来自奶酪的细菌,特别是小种类,可以显著影响人类肠道微生物群的功能.
- 从奶酪到人类的特定细菌菌株的水平传播增强了肠道微生物的功能.
- 这凸显了通过奶酪消费获得的食物微生物对健康的好处.
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