临床计算机断层扫描结肠镜上结肠外发现的预后:一个单一中心的经验
Hideto Tomimatsu1, Keita Fujimoto2, Taketo Suto2
1Radiology Department, Japanese Red Cross Gifu Hospital, Gifu City, Gifu Prefecture, Japan.
PloS one
|February 28, 2025
概括
计算机断层结肠扫描 (CTC) 结肠外发现影响患者的预后. C-RADS E4发现显著恶化了生存率,指导治疗决策,而E2和E3的影响最小.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 临床医学 临床医学
背景情况:
- 计算机断层结肠镜 (CTC) 对于结肠直肠癌查至关重要.
- 对CTC的结肠外发现 (ECF) 通常具有不确定的临床意义.
- 图形扫描结肠镜报告和数据系统 (C-RADS) 分类了ECF (E1-E4).
研究的目的:
- 为了评估C-RADS分类ECF的预后影响.
- 评估ECF对患者管理和治疗的影响.
- 分析初始和修订的ECF分类之间的一致性.
主要方法:
- 对接受CTC的103名患者进行了回顾性分析.
- 使用C-RADS (E1-E4) 进行ECF的分类.
- 卡普兰-梅尔生存分析和治疗反应的评估.
主要成果:
- 与E1-E3组合 (5.6年) 相比,C-RADS E4发现与明显更差的预后 (10.1年生存率) 相关.
- 在9名E4患者中,有6人对治疗有反应.
- E2和E3发现对治疗决策的影响有限.
- 在初始和修订的ECF分类之间观察到很高的一致性 (0.83).
结论:
- C-RADS E4 结肠外发现显著影响患者的预后和指导治疗.
- E2和E3发现对管理的影响有限,这表明需要提高诊断准确性.
- 需要进一步的研究,以完善ECF在CTC查中的解释和临床实用性.
相关概念视频
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
36
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
36
Endoscopic Procedures II: Colonoscopy
41
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
41
Assessment of the Rectum and Anus
131
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
131
Computed Tomography
4.2K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.2K
Inflammatory Bowel Disease I: Ulcerative Colitis
112
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
112
Endoscopic Procedures III: Video Capsule Endoscopy
66
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
66


