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Updated: Jun 16, 2025

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TFIIH激酶CDK7通过共同的核心转录因子网络驱动细胞增殖

Taylor Jones1, Junjie Feng2, Olivia Luyties1

  • 1Department of Biochemistry, University of Colorado, Boulder, CO 80303, USA.

Science advances
|February 28, 2025
PubMed
概括

循环素依赖酶7 (CDK7) 通过抑制核心转录因子 (TFs) 来调节细胞周期和转录. CDK7抑制对构成基因的影响比刺激反应基因更大,揭示了在增殖控制中的关键作用.

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