在Lin28介导的抑制中解码头发针结构稳定性

Qiang Zhu1, Limu Hu1, Chang Cui1

  • 1State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, P. R. China.

Biochemistry
|February 28, 2025
PubMed
概括

林28蛋白抑制了let-7微RNA (miRNA) 的生物发生,影响了癌症. 分子动力学模拟显示,针头循环是绕过Lin28抑制的关键,为癌症治疗设计提供了洞察力.

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