在延迟到达任务期间,人类杏仁体中的β频段功率调制
Shivani Sundaram1, Xiecheng Shao2, Ryan S Chung1
1Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
概括
杏仁体在运动准备和执行过程中显示β频段功率下降. 这项研究揭示了杏仁体的神经调制,扩大其已知的功能超越情绪到运动控制.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 脑部成像 脑部成像
背景情况:
- 杏仁体传统上与情绪处理和社会行为有关.
- 最近的证据表明,它通过与运动皮层的连接参与了自愿的运动控制.
- 在运动准备过程中研究杏仁体调制可以澄清它在运动处理中的作用.
研究的目的:
- 在运动准备期间使用延迟触及任务测量杏仁体中的β频段 (13-30 Hz) 调制.
- 测试运动准备和执行阶段杏仁体β频段功率下降的假设.
主要方法:
- 在11名耐药患者中利用立体电脑电图 (SEEG).
- 在延迟到达任务期间记录的贝塔频段功率.
- 分析了功率光谱密度 (PSD),并使用基于集群的换测试对任务阶段进行了比较.
主要成果:
- 在延迟 (100%的参与者,44.8%的接触者) 和响应 (90.9%的参与者,58.6%的接触者) 阶段,在杏仁体中观察到显著的β带功率下降.
- 灰质中的杏仁体接触者显示出比白质中的比 beta 波段调制显著更多 (p=0.0035).
- 根据电极横向性或参与者的性别,没有发现显著的调制差异.
结论:
- 这项研究提供了第一个证据,表明在运动准备和执行过程中,杏仁体中的β频段功率下降.
- 研究结果表明,杏仁体在自愿运动之前和运动期间表现出神经调制.
- 杏仁体的作用扩展到运动处理,超出了它在情感方面的既定功能.
相关概念视频
01:21G-Protein Gated Ion Channels
GPCRs are primarily responsible for our sense of smell, taste, and vision. The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
Sensory organs,...
Sensory organs,...
01:22Muscle Stimulation Frequency
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
01:17Cut-off Frequency of BJT
Cut-off frequencies in Bipolar Junction Transistors (BJTs) mark the transition between the signal's pass band and stop band, influencing their performance in amplifying or attenuating frequencies. These frequencies are crucial for designing BJTs to meet specific operational requirements in electronic circuits.
Alpha Cut-Off Frequency: Pertinent to the common-base configuration, the alpha cut-off frequency defines the upper-frequency limit at which the current gain, alpha, remains stable. As...
Alpha Cut-Off Frequency: Pertinent to the common-base configuration, the alpha cut-off frequency defines the upper-frequency limit at which the current gain, alpha, remains stable. As...
01:24Frequency-Domain Interpretation of PD Control
Proportional-Derivative (PD) controllers are widely used in fan control systems to improve stability and performance. A fan control system can be effectively represented using a Bode plot to illustrate the impact of a PD controller through its transfer function. The Bode plot visually conveys how PD control modifies the fan's response across various frequencies, providing a frequency domain interpretation of the controller's behavior.
The proportional control gain, combined with the system's...
The proportional control gain, combined with the system's...
01:21Time and frequency -Domain Interpretation of Phase-lag Control
Phase-lag controllers are widely used in control systems to improve stability and reduce steady-state errors. A dimmer switch controlling the brightness of a light bulb serves as a practical example of phase-lag control, gradually adjusting the bulb's brightness. Mathematically, phase-lag control or low-pass filtering is represented when the factor 'a' is less than 1.
Phase-lag controllers do not place a pole at zero, but instead influence the steady-state error by amplifying any finite,...
Phase-lag controllers do not place a pole at zero, but instead influence the steady-state error by amplifying any finite,...
01:28Load-frequency control
Load-frequency control (LFC) is vital for maintaining power system stability, ensuring that frequency and power flows remain within acceptable limits during load changes. Turbine-governor control eliminates rotor accelerations and decelerations following load changes. However, a steady-state frequency error persists when the change in the turbine-governor reference setting is zero. In an interconnected power system, each area agrees to export or import a scheduled amount of power through...