全餐和部分餐替代品对肥胖的影响:随机对照试验的系统审查和元分析
Mingguang Yan1, Yan Hu2, Weibing Yin1
1Department of Clinical Laboratory, The First People's Hospital of Shangqiu, Shangqiu, China.
Critical reviews in food science and nutrition
|February 28, 2025
概括
这项研究发现,MR显著降低体重,BMI,脂肪质量和腰围. 虽然MRs促进体重减轻,但它们并没有显著影响瘦素水平.
科学领域:
- 代谢研究研究 代谢研究
- 肥胖研究 肥胖研究
- 营养科学 营养科学
背景情况:
- 调查各种干预措施对人类测量和代谢标志物的影响.
- 了解特定因素在体重管理和身体构成中的作用.
研究的目的:
- 综合评估MRS对体重,BMI,脂肪质量,腰围和瘦素的影响.
- 综合现有关于MR和它们对肥胖相关参数的影响研究的证据.
主要方法:
- 在五个数据库中使用定义的关键词进行系统的文献搜索.
- 随机效应模型分析,以计算聚合加权平均差异和95%置信区间.
- 包括七十个相关的研究进行元分析.
主要成果:
- 在MRs之后观察到体重 (WMD: -3.35公斤),BMI (WMD: -1.12公斤/米2),脂肪质量 (WMD: -2.77公斤) 和腰围 (WMD: -2.82厘米) 的显著减少.
- 没有检测到MRs对叶丁水平的统计学意义上的影响 (WMD: -3.37 ng/mL).
- 亚组分析显示,与部分MR相比,总MR对人类学因素的影响更大.
结论:
- 与其他生活方式修改相结合,MR在实现显著减肥方面是有效的.
- MRs对与代谢健康相关的关键人体指标产生积极影响.
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