评估全球喘倡议指南更新在商业保险,基于价值的护理人口中的采用情况
Lindsey M McInturff1, Spenser Smith1
1Blue Cross and Blue Shield of North Carolina, Durham.
Journal of managed care & specialty pharmacy
|February 28, 2025
概括
该研究发现,使用吸入性皮质类固醇 (ICSs) -formoterol作为喘缓解剂可使喘恶化减少25.6%. 然而,这种喘治疗导致药房和总成本增加,尽管医疗费用较低.
科学领域:
- 肺部病理学 肺部病理学
- 药物经济学 药物经济学
- 现实世界的证据研究研究.
背景情况:
- 喘是美国普遍存在的慢性呼吸道疾病,造成了巨大的经济成本.
- 更新的"全球喘倡议"指南建议吸入性皮质类固醇 (ICSs) - 形式醇作为首选的喘缓解剂.
- 关于本指南更新的临床和经济影响的现实数据有限.
研究的目的:
- 评估在采用ICSs-formoterol作为首选缓解剂之前和之后的真实世界喘结果和成本.
- 评估更新的喘治疗指南对患者健康和医疗保健支出的影响.
主要方法:
- 一项回顾性,观察性队列研究分析了商业保险成员的索赔数据,年龄为6-65岁,患有喘.
- 这项研究比较了12个月的预期期和12个月的后期,在开始使用ICSs-formoterol吸入器后.
- 主要结局包括每年喘恶化和喘特异性药房,医疗和总成本.
主要成果:
- 年平均喘恶化减少了25.6% (0.347到0.258,P=0.028).
- 平均喘特异性药房费用大幅增加 (474美元至1,796美元,P<0.001).
- 平均喘总费用大幅上 (1505美元至2567美元,P<0.001),而平均医疗费用则下降 (1031美元至771美元,P=0.031).
结论:
- 启动ICS-formoterol用于喘管理与减轻恶化相关,但药房和总成本增加.
- 尽管药费增加,但与喘护理相关的医疗费用下降.
- 卫生计划应考虑促进遵守指导方针的策略,并进一步减少喘恶化.
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