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Updated: May 24, 2025

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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由CYP3A4调解的伊布迪拉斯特的代谢激活和细胞毒性

Lingwen Dong1, Xialing Hao1, Minglu Liu1

  • 1Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, People's Republic of China.

Archives of toxicology
|February 28, 2025
PubMed
概括

用于神经疾病的IBD可能会导致肝损伤. 这项研究表明,IBD代谢过程中形成的活性环氧化物中间体与这种肝毒性有关,为不良影响提供了洞察力.

关键词:
在 CYP3A4 中.细胞毒性 细胞毒性环氧化物 是一种氧化物.在Ibudilast上使用.代谢激活的代谢激活

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