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Updated: May 24, 2025

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
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Published on: January 22, 2019

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未连接的HIV-1RNA的核保留作为潜伏期的可逆转录后阻断

Agnieszka Dorman1,2, Maryam Bendoumou3, Aurelija Valaitienė4

  • 1Laboratory of Molecular Virology, Malopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland.

Nature communications
|February 28, 2025
PubMed
概括

通过Rev,MATR3和MTR4对HIV-1RNA出口的转录后调节会影响病毒的活性. 这项研究揭示了ART治疗个体的可逆核出口阻断,这对于艾滋病毒治愈策略至关重要.

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