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Updated: May 24, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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KEAP1-NRF2/HO-1通路促进了精神分裂症患者的铁和神经损伤

Feng Zhu1, Tangqun Dan1, Shuguang Hua1

  • 1Department of Psychiatry, The Second Affiliated Hospital of Hubei University of Science and Technology, Xianning, Hubei, China.

Brain and behavior
|February 28, 2025
PubMed
概括

精神分裂症与KEAP1水平降低有关,增加铁亡和神经元损伤. 恢复脑细胞中的KEAP1表达可能为这种神经系统疾病提供治疗点.

关键词:
KEAP1‐NRF2/HO‐1 的情况.铁性化 (ferroptosis) 是一种由hiPSC衍生的皮质内部神经元.神经元损伤是指神经元受伤.氧化应激是一种氧化应激.精神分裂症是一种精神分裂症.

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