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Updated: May 24, 2025

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快速高效的方法,并行构建目标的外体和甲基组单链DNA测序库

Eunhye Kim1, Sinae An1,2, Heerak Ahn2

  • 1Department of Pharmacy, School of Pharmacy and Institute of New Drug Development, Jeonbuk National University, Jeonju, 54907, Republic of Korea.

Scientific reports
|February 28, 2025
PubMed
概括

我们开发了一种高效的工作流程,用于从有限的,受损的DNA中构建并行基因组和表观基因组测序库. 这种方法可以准确地识别儿科脑癌样本中的突变和甲基化,即使是来自老年甲固定组织的样本.

关键词:
异源 (exome) 是指外源 (exome) 的一个部分.嵌入式法固定的法 (FFPE) 嵌入式甲基组组是指甲基组组中的一种.儿科大脑癌症 儿科大脑癌症单链DNA库是一个单链DNA库.

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