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患有或没有夜间高血压的CKD患者的血压变化
Artemios G Karagiannidis1, Marieta P Theodorakopoulou2, Fotini Iatridi1
1First Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Journal of human hypertension
|February 28, 2025
概括
慢性病 (CKD) 患者的夜间高血压与24小时和白天期间更高的血压变化 (BPV) 有关. 这种增加的BPV可能会导致这些人的心血管风险增加.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 高血压研究 高血压研究
背景情况:
- 夜间高血压在慢性病 (CKD) 中很常见,也是心血管事件的重要预测因素.
- 升高的血压变化 (BPV) 也独立地与慢性病患者的不良心血管结果有关.
- 之前的研究没有专门研究晚间高血压和没有晚间高血压的CKD患者之间的短期BPV差异.
研究的目的:
- 为了研究和比较CKD患者与没有夜间高血压之间的短期血压变化 (BPV) 指数.
- 确定是否存在24小时,白天和夜间BPV的差异,与CKD中夜间高血压的存在有关.
主要方法:
- 包括96名CKD患者 (73人患有夜间高血压,23人没有).
- 使用了24小时的门诊血压监测.
- 计算的BPV指数包括标准偏差 (SD),加权SD (wSD),变化系数 (CV) 和24小时,白天和夜间期间的缩 (SBP) 和腹缩血压 (DBP) 的平均真实变化率 (ARV).
主要成果:
- 与没有夜间高血压的患者相比,SBP和DBP的24小时wSD和ARV较高.
- 在夜间高血压患者中观察到SBP和DBP的较高白天SD和ARV.
- 两组之间没有发现夜间BPV指数的显著差异.
结论:
- 晚间高血压的CKD患者表现出显著更高的24小时和白天血压变化.
- 由于夜间BPV没有显著差异,这表明在清醒时段的变化增加有助于该人群的心血管风险.
- 血压升高,特别是在白天,可能是导致晚间高血压的心血管风险增加的一个关键因素.
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