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Updated: May 24, 2025

Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy
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Published on: December 17, 2019

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通过CAR介导的目标识别限制了TCR和CAR双受体编辑T细胞的TCR介导的目标识别

Tassilo L A Wachsmann1, Teuntje Poortvliet1, Miranda H Meeuwsen1

  • 1Department of Hematology, Leiden University Medical Center, 2333ZA Leiden, the Netherlands.

Molecular therapy : the journal of the American Society of Gene Therapy
|March 1, 2025
PubMed
概括

针对多个髓瘤抗原的双重工程T细胞 (TRaCR) 显示双重特异性,但优先参与CAR. 这种CAR偏好可以导致异质多发性骨髓瘤中的瘤细胞存活,因此需要对这种方法保持谨慎.

关键词:
这就是为什么BCMABCMABCMA.在CAR T细胞中,CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19在TCR工程T细胞疗法中.抗原逃逸的方法是什么?细胞疗法是细胞疗法.组合疗法 组合疗法多抗原向的多抗原向.多发性骨髓瘤是多发性骨髓瘤的一种.

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