通过儿科健康信息系统 (PHIS) 数据库评估先天性梅毒的诊断准确性,使用青素给药数据
John M Flores1, Natalie Grills2, Jason M Kane3
1Department of Pediatrics, Section of Pediatric Infectious Diseases, Comer Children's Hospital, University of Chicago, Chicago, IL, USA.
International journal of STD & AIDS
|March 1, 2025
概括
在全国范围内,先天性梅毒 (CS) 正在增加. 许多因疑似CS而接受青素治疗的婴儿缺乏正式诊断,这表明这种不断增长的流行病的诊断不足.
科学领域:
- 儿童传染病 儿童传染病
- 公共卫生流行病学 流行病学
- 医疗保健数据分析数据分析
背景情况:
- 疾病预防控制中心报告的先天性梅毒 (CS) 病例全国增加 (2012-2021年为773%).
- 需要评估儿童三级保健机构中CS的诊断准确性.
研究的目的:
- 为了评估先天性梅毒诊断的准确性,使用青素的管理和ICD-10计费数据.
- 确定青素在婴儿中的使用是否与报告的CS流行病学趋势相关.
主要方法:
- 这是一项回顾性队列研究,涉及49家美国主要儿童医院.
- 分析了30天以下的婴儿服用青素的情况,不包括其他常见感染.
- 与ICD-10编码诊断相关联的治疗数据.
主要成果:
- 2290名婴儿接受了青素治疗;49.3%的婴儿缺乏CS诊断.
- 95.3%的被诊断为CS的婴儿接受了超过1天的青素.
- 37.9%的没有CS诊断的婴儿被确诊,但接受过1天以上的青素治疗.
结论:
- 显著数量的婴儿在没有公布诊断的情况下接受了青素和CS工作,这表明可能低估了疾病.
- 解决儿科和孕产妇医疗保健中的社会经济差异.
- 强调需要准确地描述不断增长的CS流行病.
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