短期暴露于环境颗粒物污染和外科手术的结果
Wendelyn M Oslock1, Lauren Wood2, Arundhati Sawant2
1Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama; Department of Quality, Birmingham Veterans Affairs Medical Center, Birmingham, Alabama.
The Journal of surgical research
|March 1, 2025
概括
短期暴露于细颗粒物 (PM2.5) 空气污染与结直肠手术后更长的住院时间有关. 这项研究强调了空气质量对手术恢复和患者结果的影响.
科学领域:
- 环境健康 环境健康
- 手术结果研究研究.
- 公共卫生 公共卫生
背景情况:
- 颗粒物小于2.5微米 (PM2.5) 可能引发炎症和细胞损伤.
- 以前的研究将PM2.5与尾炎和炎症性肠病联系起来,但其对手术恢复的影响尚不清楚.
研究的目的:
- 调查成人结直肠外科手术患者的短期PM2.5暴露和手术结果之间的关联.
- 探索空气污染对逗留时间,并发症和再录取的影响.
主要方法:
- 对1038名结直肠手术患者 (2006-2021) 的回顾性队列研究.
- 将患者数据与入院当天的EPA PM2.5度联系起来.
- 利用环境正义指数来考虑社会和环境压力因素.
- 使用多变量回归分析了停留时间,并发症和再入院情况.
主要成果:
- 住院当天更高的PM2.5暴露与更长的住院时间 (LOS) 有显著的关联.
- 对LOS的事件率比率为1.12对于中度升高的暴露和1.37对于高PM2.5暴露.
- 污染组之间的未调整结果没有显著差异.
结论:
- 短期暴露于环境空气污染,特别是PM2.5,新鲜地与手术恢复时间长 (较长的LOS) 相联系.
- 这项研究是第一个将环境正义指数纳入外科研究以控制健康决定因素的研究.
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