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Updated: May 24, 2025

Ileectomy-induced Bile Overaccumulation in Mouse Intestine
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来自ilicis rotundae皮层的triterpenoids通过影响胆汁酸-肝肠FXR轴来改善超脂血症

Wei Zeng1, Mengjia Sun1, Jiamin Cao1

  • 1State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China; Chinese Medicine Guangdong Laboratory, Guangdong Hengqin, 519000, PR China.

Phytomedicine : international journal of phytotherapy and phytopharmacology
|March 1, 2025
PubMed
概括

来自Ilicis Rotundae Cortex (IRC) 的总三烯酸 (TT) 提取物有效地降低了超脂症小鼠的血脂水平. 这项研究揭示了它的机制,包括激活肠道的FXR-FGF15/19通路,改善胆酸代谢和减少肝损伤.

关键词:
胆酸是什么意思 胆酸是什么意思在 FXR 和 FXR 之间.肝肠轴 肝肠轴 肝肠轴超脂血症是因为超脂血症总的三基化物.

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