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Updated: May 24, 2025

Site Specific Lysine Acetylation of Histones for Nucleosome Reconstitution using Genetic Code Expansion in Escherichia coli
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氨酸化是一种维生素C衍生的蛋白质修饰,可增强STAT1介导的免疫反应

Xiadi He1, Qiwei Wang2, Xin Cheng3

  • 1Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, National Clinical Research Center for Metabolic Diseases (Shanghai), Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Lifecycle Health Management Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Cell
|March 1, 2025
PubMed
概括

维生素C (vitC) 通过改变氨酸残留物产生一种新的修饰,称为化. 这一过程通过增强干扰素信号和免疫细胞识别来增强抗瘤免疫力.

关键词:
一个国家免疫反应蛋白质的修饰维生素C化

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