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Updated: May 24, 2025

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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由AECII衍生出的miR-21a-5p外体通过向和调节PGAM5-介导的亡症来减轻HALI

Ping Yuan1, Yunliang Cao2, Yingcong Ren3

  • 1Medical College of Soochow University, 215123 Suzhou, Jiangsu, China; The Affiliated Hospital of Zunyi Medical University, 563000 Zunyi, Guizhou, China; Department of Pediatrics, Guizhou Children's Hospital, 563000 Zunyi, Guizhou, China.

Cellular signalling
|March 1, 2025
PubMed
概括

肺上皮细胞外体中的MicroRNA-21a-5p通过抑制PGAM5亡途径,防止过氧性急性肺损伤. 这表明外体miR-21a-5p作为肺部保护的潜在治疗点.

关键词:
外基因组是外基因组的组成部分.过氧性急性肺损伤是什么?尸体灭 (Necroptosis) 是一种死亡的过程.这是一个PGAM5PGAM5.文字转录学 (Transcriptomics) 是一个学科.在 miR-21a-5p 中.

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