急性缺血性中风的多发症及其对短期死亡率的影响:智利全国数据库分析
Francisca González1, Ma Ignacia Allende2, Marilaura Nuñez2
1Centro de Estudios Clínicos, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile; Facultad de Ciencias de la Salud Blanquerna, Universitat Ramón Llull, Barcelona, Spain.
概括
在急性缺血性中风 (AIS) 后,多病症很常见,特别是心脏代谢状况,增加了住院死亡率. 在中风治疗中,以多病症为重点的方法对于改善患者的治疗结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 多发病症显著影响疾病预后,但其在急性缺血性中风 (AIS) 后在发展中国家的作用仍未得到充分研究.
- 了解多病态模式对于改善不同人群中风护理至关重要.
研究的目的:
- 在AIS患者中表征多病症模式.
- 确定智利AIS后多发病率和住院死亡率之间的关联.
主要方法:
- 2019年智利诊断相关组数据库的回顾性分析.
- 包括被诊断患有AIS的住院成年患者 (ICD-10代码I63).
- 使用后勤回归模型来评估多病症 (≥2种健康状况) 与住院死亡率之间的关联,并对混因素进行调整.
主要成果:
- 在10,440名AIS患者中,73.7%的患者表现出多病症,受年龄,女性性别和较低社会经济地位的影响.
- 心脏代谢多病症显著增加了住院死亡率 (OR 1.39,95% CI 1.16-1.66).
- 患有缺血性心脏病的5期慢性病呈现出最高的死亡风险 (OR 4.20,95% CI 1.58-11.16).
结论:
- 在AIS患者中,多病症很普遍,年龄和性别影响了并发症的组成.
- 心脏代谢多病症是AIS后医院死亡率增加的关键预测因素.
- 建议在中风护理管理中实施以多病症为中心的策略,以提高患者的治疗结果.
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