结核二次性血细胞性淋巴细胞细胞瘤 (HLH):一个病例系列
Chitra Veluthat1, Kavitha Venkatnarayan1, Uma Maheswari1
1Department of Pulmonary Medicine, St. John's National Academy of Health Sciences, Bengaluru, India.
The Indian journal of tuberculosis
|March 1, 2025
概括
血细胞淋巴细胞细胞瘤 (HLH) 是一种严重的免疫过度反应. 结核病 (TB) 可以导致HLH,导致由于重叠的症状导致误诊,特别是在呼吸器重症监护病房.
科学领域:
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 血细胞淋巴细胞瘤 (HLH) 是一种危及生命的免疫失调.
- HLH具有与败血症重叠的临床和生化特征,增加了误诊风险.
- 结核病 (TB) 是HLH的重要传染性触发因素,与高死亡率有关.
研究的目的:
- 突出结核病相关的HLH (TB-HLH) 的诊断挑战.
- 在呼吸器重症监护环境中呈现TB-HLH病例系列.
- 强调在HLH诊断中考虑结核病的重要性.
主要方法:
- 追溯案例系列分析.
- 对四名TB-HLH患者的临床数据和诊断工作报告的审查.
- 在第三级护理呼吸器重症监护病房的呈现分析.
主要成果:
- 四例TB-HLH病例被确定并在呼吸器ICU接受治疗.
- 由于症状与其他疾病重叠,人们注意到诊断延迟.
- 结核病被证实是这些患者HLH的潜在原因.
结论:
- 结核病相关的HLH带来了重大的诊断挑战.
- 早期识别和诊断TB-HLH对于患者的治疗结果至关重要.
- 在HLH患者中,对结核病的提高警是有必要的,特别是在流行地区.
相关概念视频
Pulmonary Tuberculosis II
208
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
208
Pulmonary Tuberculosis III
291
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
291
Pulmonary Tuberculosis I
215
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
215
Pulmonary Tuberculosis V
163
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
163
Pulmonary Tuberculosis IV
128
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
128


