在腹腔外科手术后术后妄的预防性干预 - - 随机试验的系统审查和元分析
J Jensen1, K Thorhauge1, C L Petri2
1Department of Gastrointestinal and Hepatic Diseases, Copenhagen University Hospital - Herlev and Gentofte, Denmark; Emergency Surgery Research Group Copenhagen (EMERGE Cph), Copenhagen University Hospital - Herlev and Gentofte, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
预防性干预可显著降低49%的腹内手术后手术后 Delirium (POD) 的风险. 实施这些策略对于改善手术环境中的患者结果至关重要.
科学领域:
- 手术成果研究的研究结果.
- 老年医学 老年医学
- 麻醉学 麻醉学
背景情况:
- 手术后妄 (POD) 是手术后的一个主要并发症,导致住院时间更长,成本增加和死亡率更高.
- 预计POD的发病率将增加,因为老年人口越来越多,需要有效的预防方法.
- 这项研究侧重于腹内外科手术患者,以评估POD预防策略.
研究的目的:
- 评估预防性干预措施在减少术后痴呆症 (POD) 的发生率方面的有效性.
- 分析这些干预措施对死亡率和住院时间等次要结果的影响.
主要方法:
- 一个系统的审查和元分析,遵循PRISMA指南.
- 包括来自主要数据库 (MEDLINE,Embase,Cochrane Library) 的随机对照试验 (RCT).
- 使用随机效应元分析对POD发病率的分析.
主要成果:
- 分析了16个具有4060名参与者的RCT.
- 预防性干预表明POD风险降低了49% (RR:0.51;95% CI:0.36至0.73).
- 没有发现对30天/180天的死亡率或住院时间长度有重大影响;亚组分析表明在腹腔镜手术中疗效更大.
结论:
- 预防性干预是有效的降低POD在腹内手术后的发病率.
- 对于高风险的手术患者,建议采用标准化查和干预方案.
- 未来的研究应该完善预防策略,并调查POD机制.
更多相关视频
03:42Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
Published on: March 15, 2024
04:01Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis
Published on: September 8, 2022
相关概念视频
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Stages of General Anesthesia
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
