出生于患有超重复妊娠症的母亲的后代的学校成绩
Martha Veber Fogh1, Rikke Wiingreen2, Anne Ostenfeld3
1Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
American journal of obstetrics and gynecology
|March 2, 2025
概括
怀孕期间暴露于妊娠中高血压的暴露与后代的学业成绩较低有轻微的关联. 然而,兄弟姐妹之间的比较表明家庭因素,而不是疾病本身,可能会解释这些差异.
科学领域:
- 产科和妇科 产科和妇科
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 妊娠激增 (HG) 是一种严重的妊娠并发症,影响高达3%的怀孕.
- HG对儿童认知发育的影响在很大程度上是未知的.
研究的目的:
- 调查子宫内HG暴露与后代学校成绩之间的关联.
- 为了比较暴露于HG的儿童与未暴露的同行和兄弟姐妹之间的学校成绩.
主要方法:
- 基于人口的队列研究,包括1986-2005年间出生的1,162,249名丹麦儿童.
- 包括12720名儿童在子宫内接触到母亲的HG诊断.
- 通过使用回归模型和兄弟分析,通过平均分数平均和低学校成绩率评估学校成绩.
主要成果:
- 暴露于HG的后代在学校成绩较低的几率更高 (aOR 1.19) 和较低的平均成绩点平均值 (-0.18).
- 调整后的分析考虑了出生年份,母亲和社会经济因素.
- 兄弟姐妹内部分析显示,暴露和未暴露的兄弟姐妹之间的学校成绩没有显著差异.
结论:
- 在子宫内HG暴露和较差的学校成绩之间存在一个小的关联.
- 兄弟姐妹分析表明家族因素,而不是HG本身,可能解释了观察到的关联.
- 需要进一步的研究来阐明遗传和共同的环境因素的作用.
更多相关视频
06:39Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
3.0K
03:19Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
344
相关概念视频
02:07Oogenesis
63.3K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.3K
02:57Meiosis vs. Mitosis
52.2K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
52.2K