中程节奏QRS作为心脏事件的独立负面预测器 - 右心室节奏影响
Yuichiro Miyazaki1,2, Kohei Ishibashi1, Nobuhiko Ueda1
1Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center.
概括
节奏QRS持续时间为149毫秒或更短,与心脏起器植入后心脏事件的减少有关. 这一发现表明成功的右心室节奏策略的目标.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 节奏QRS持续时间对患者结果的长期影响仍然不确定.
- 评估节奏QRS持续时间和心脏事件之间的关系对于优化心脏起器治疗至关重要.
研究的目的:
- 调查节奏QRS持续时间与心脏事件发生率之间的关联.
- 为了确定节奏QRS持续时间是否可以预测心脏起器患者的不良心脏结果.
主要方法:
- 分析了2018年至2021年间接受心脏起器植入的187名患者的队列.
- 对心脏事件进行了监测,平均随访时间为972天.
- 统计分析包括ROC曲线,Kaplan-Meier和Cox危险模型.
主要成果:
- 经历心脏事件的患者与没有事件 (148±17毫秒) 的患者相比,节奏QRS持续时间显著更长 (162±17毫秒).
- 149毫秒的节奏QRS持续时间被确定为预测心脏事件的最佳时间 (AUC=0.72).
- 中程节奏QRS持续时间 (≤149毫秒) 与更好的长期结果和降低心脏事件风险 (HR=0.28) 相关.
结论:
- 节奏QRS持续时间为149毫秒或更短与心脏事件的显著减少有关.
- 这个持续时间可以作为一个有价值的目标指数,用于成功的右心室节奏.
- 优化节奏QRS持续时间可以改善心脏起器患者的长期预后.
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