多发性骨髓瘤患者的口腔血瘤:报告了18例病例
Lama Alabdulaaly1, Maryam Jessri1, Nathaniel Treister2
1Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, MA, USA; Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA.
概括
口腔血瘤是多发性骨髓瘤 (MM) 的罕见表现,经常影响牙,并可能导致疼痛和出血. 这项研究强调了MM患者口腔血细胞瘤的常见部位和不良预后.
科学领域:
- 口腔医学是指口腔医学.
- 血液学 血液学 血液学
- 在瘤学瘤学.
背景情况:
- 血瘤是一种恶性血细胞瘤,偶尔与多发性骨髓瘤 (MM) 相关.
- 口腔受血细胞瘤的影响很少见,影响口腔粘膜和骨.
研究的目的:
- 描述多发性骨髓瘤患者口服血细胞瘤的临床特征和结果.
- 在MM患者中识别常见的口腔部位和呈现血细胞瘤症状.
主要方法:
- 在口腔医学诊所诊断出口腔血瘤的患者的回顾性研究.
- 从2007年到2024年收集的数据,包括患者人口统计数据,临床表现,参与地点,治疗和生存率.
主要成果:
- 分析了26名口服血细胞瘤的18名患者;中位数年龄为60.5岁,女性为72.3%.
- 常见的症状包括疼痛和出血. 在10名患者中发生了关节 (骨) 参与,而8名患者患有软组织疾病.
- 牙是最常见的部位 (50.0%),其中38.5%呈现口舌传播. 超过90%的患者在平均5个月内死亡.
结论:
- 多发性骨髓瘤患者可以呈现口服血细胞瘤,主要是在牙上.
- 口腔和舌腔参与是常见的,MM患者的口腔血清细胞瘤预后不佳.
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