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Updated: May 24, 2025

Visualization of Endogenous Mitophagy Complexes In Situ in Human Pancreatic Beta Cells Utilizing Proximity Ligation Assay
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调控性ChREBP/14-3-3复合物的分子剂保护β细胞免受葡萄糖脂毒性影响

Liora S Katz1, Emira J Visser2, Kathrin F Plitzko3

  • 1Diabetes, Obesity and Metabolism Institute and Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Nature communications
|March 2, 2025
PubMed
概括

科学家们开发出一种新的分子,以稳定蛋白质相互作用,保护人类β细胞免受损伤,在2型糖尿病模型中. 这种方法为糖尿病治疗提供了一个新的治疗策略.

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