在呼吸道 papilomatosis 患者的操作频率和年龄之间的非线性关系
Weili Kong1, Ren Jia1, Hailing Gu1
1Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
概括
患有呼吸道 papilomatosis (RP) 的年轻患者需要显著更多的手术. 年龄是一个关键因素,8.2岁是一个显著的拐点,影响了RP儿童的手术频率.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 儿科手术 儿科手术
- 在瘤学瘤学.
背景情况:
- 呼吸道乳头瘤 (RP) 是一种良性呼吸道瘤,通常是由人类乳头瘤病毒 (HPV) 引起的.
- 患有RP的患者通常会接受多次手术干预.
- 有限的研究存在于患者年龄对RP手术频率的影响.
研究的目的:
- 调查患者年龄与呼吸道乳头瘤病所需的手术数量之间的关系.
- 确定影响RP患者手术频率的关键年龄值.
- 为改善RP的临床管理和预后评估提供数据.
主要方法:
- 在2000年至2022年间接受手术的676名RP患者的回顾性分析.
- 患者的分层分为儿科 (≤18岁) 和成人 (>18岁) 组.
- 应用平滑曲线适配,值效应分析和通用添加模型来评估与年龄相关的手术频率.
主要成果:
- 观察到年龄和RP手术数量之间存在显著的非线性关系.
- 18岁以下的患者每年需要平均5.5次手术,而成年人需要1.7次.
- 在8.2岁时确定了一个关键的转折点;手术频率随着年龄的增长而下降.
结论:
- 年龄是呼吸道 papilomatosis 手术频率的一个重要决定因素.
- 年轻的患者,特别是年龄在8.2岁以下的患者,需要更频繁的手术干预.
- 这些发现支持根据患者年龄量身定制的治疗策略和预后评估.
相关概念视频
01:19Factors Affecting Pulmonary Ventilation
3.2K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
3.2K
01:23Chronic Pharyngitis
16.7K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
16.7K