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Updated: May 24, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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在与癌症相关的基因促进体中识别G-四方体相互作用蛋白

Simona Marzano1, Gabriella Pinto2,3, Anna Di Porzio1

  • 1Department of Pharmacy, University of Naples Federico II, 80131, Naples, Italy.

Communications chemistry
|March 2, 2025
PubMed
概括

研究人员确定了86种与G-四重复相关的蛋白质 (G4RPs),包括一些新的蛋白质,这些蛋白质与与癌症相关的DNA序列相互作用. 这一发现有助于更好地理解癌症中的G-四重复和潜在的治疗点.

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