与男性发生性关系的男性 (MSM):系统性审查
G M de Jong1,2, S C van der Boor1, C van Bokhoven3
1Centre for Infectious Disease Control (LCI), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
BMC infectious diseases
|March 2, 2025
概括
在全球范围内发现了社区获得的甲素耐药黄金葡萄球菌 (CA-MRSA) 疫情. 虽然本质上与与男性发生性关系 (MSM) 的男性无关,但特定的行为会增加该人口中的CA-MRSA风险.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 社区获得的甲素耐药黄金葡萄球菌 (CA-MRSA) 爆发是一个全球性问题.
- 与男性发生性关系的男性 (MSM) 中CA-MRSA感染率升高表明潜在的性传播.
- 本综述评估了MSM中CA-MRSA的流行率和风险因素,以了解其对公共卫生的影响.
研究的目的:
- 系统地审查关于CA-MRSA殖民和MSM感染的文献.
- 在这个人群中识别与CA-MRSA相关的风险因素.
- 评估CA-MRSA殖民和感染在MSM中的流行率.
主要方法:
- 在Embase.com (Embase和Medline) 的系统文献搜索,截至2024年1月19日.
- 包括符合特定标准的英语文章.
- 独立审查和数据提取由多个审查者来确保准确性.
主要成果:
- 从54篇选文章中,包括了18项研究.
- 在美国和日本的MSM中发现了三个不同的CA-MRSA集群.
- 仅仅是MSM身份并不是风险因素;然而,静脉注射药物使用和高风险性行为会增加风险.
结论:
- 在患有皮肤感染的MSM中对CA-MRSA的临床意识至关重要.
- 根除策略和非药物干预对具有CA-MRSA集群的性网络至关重要.
- 由于数据有限,需要对全球流行和性网络中的传播动态进行进一步的研究.
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