IRF1是一个核心的转录调节电路成员,通过调节脂质代谢来促进AML的进展

Fenli Zhang1, Zhiheng Li2, Fang Fang2

  • 1Department of Pediatrics, Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Street, Yunyan District, Guiyang, 550000, Guizhou, China.

概括

这项研究确定IRF1是急性髓性白血病 (AML) 的关键转录因子. IRF1形成了一个促进AML进展的调节电路,并影响脂质代谢,影响癌细胞存活率.

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