神经疾病和维生素B在儿童中的水平12
1Department of Pediatric Neurology, Giresun University, Giresun, Turkey.
Journal of child neurology
|March 3, 2025
概括
在患有神经系统疾病,特别是的儿童中,维生素B12水平升高更为常见. 需要进一步的研究来了解儿童神经病患者的这种关联.
科学领域:
- 儿科神经学 儿科神经学
- 临床生物化学 临床生物化学
背景情况:
- 维生素B12缺乏是神经症状的已知原因之一.
- 越来越多地观察到维生素B12水平升高,可能与神经疾病有关.
- 在儿科神经疾病中了解维生素B12水平至关重要.
研究的目的:
- 为了评估被诊断患有神经系统疾病的儿童的维生素B12水平.
- 为了比较儿科神经病患者和一般儿科患者的维生素B12水平.
- 研究患有神经疾病的儿童维生素B12水平升高的患病率和潜在关联.
主要方法:
- 从2000年到2023年在一个中心对儿科维生素B12水平的回顾性分析.
- 排除具有不完整数据或维生素补充剂的患者.
- 根据维生素B12水平 (<200,201-660,661-1000,>1000 pg/mL) 和诊断的评估对患者进行分类.
主要成果:
- 与一般儿科患者相比,儿科神经病患者的维生素B12水平升高 (>660 pg/mL) 更频繁.
- 在338名B12水平升高的患者中,平均水平为894.7 pg/mL.
- 在持久高维生素B12水平的患者中,是最常见的诊断,其次是早产,脑,自闭症,智力障碍和语言延迟.
结论:
- 维生素B12水平升高与儿科神经系统疾病,特别是有关.
- 高维生素B12在儿科神经学中的临床意义和潜在机制需要进一步研究.
- 这项研究突出了小儿神经疾病中潜在的生物标志物或相关因素.
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