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相关概念视频

Obesity01:24

Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Alzheimer's Disease: Overview01:26

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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相关实验视频

Updated: May 24, 2025

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
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肥胖与渐进性大脑结构变化有关.

Huiling Zhou1,2, Yang Hu1,2, Guanya Li1,2

  • 1Center for Brain Imaging, School of Life Science and Technology, Xidian University & Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi'an, China.

Obesity (Silver Spring, Md.)
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PubMed
概括
此摘要是机器生成的。

肥胖的进展与与奖励和抑制控制相关的大脑区域的灰质体积减少有关. 这些结构性大脑变化为肥胖治疗提供了新的见解.

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科学领域:

  • 神经科学是一个神经科学.
  • 放射学 放射学是一门学科.
  • 公共卫生 公共卫生

背景情况:

  • 肥胖是一个日益严重的全球健康问题.
  • 大脑结构的改变可能是肥胖相关行为的基础.
  • 了解这些变化对于有效的干预至关重要.

研究的目的:

  • 研究肥胖进展和大脑结构变化之间的关系.
  • 为了确定受增加体质指数 (BMI) 影响的特定大脑区域.

主要方法:

  • 磁共振成像 (MRI) 用于分析大脑结构.
  • 包括258名超重或肥胖的参与者和74名正常体重的对照.
  • 使用因果结构共变网络来研究渐进性影响.

主要成果:

  • 随着BMI的增加,观察到灰质体积的减少,起源于尾状核,轨道前皮层和岛屿.
  • 这些变化进展到海马体,副海马圈,前体和背侧前额皮层.
  • 尾状核和中间轨道前皮层对其他受影响的大脑区域产生因果影响.

结论:

  • 肥胖的脑灰质变化可能从奖励处理区域开始,扩散到参与控制和记忆的区域.
  • 这些发现为针对肥胖的临床干预提供了新的视角.