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Updated: Jul 31, 2026

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles
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Published on: January 4, 2012

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加尔纳克终端覆盖的多 (β-氨基) 具有屏蔽侧链,用于高效的基因传递

Xinlong Liu1, Yimeng Li1, Xinhua Liu2

  • 1School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200240, China.

Small methods
|March 3, 2025
PubMed
概括

研究人员开发了新型的聚β-氨基 (PBAE) 与N-乙黄胺 (GalNAc) 进行高效的基因疗法. 这些GalNAc-PBAE向肝脏,减少纤维化,并改善小鼠的肝功能.

关键词:
在 GalNAc 连接物中,肝细胞生长因子 肝细胞生长因子肝脏纤维化 肝脏纤维化输送等离子体的输送聚-β-氨基) 是一种聚-β-氨基.

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