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Updated: May 24, 2025

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
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在肝癌和免疫治疗中NOTCH1的两面

Jiani Zhu1,2, Ekaterina K Koltsova1,2

  • 1Department of Medicine, Cedars-Sinai Medical Center, Cedars-Sinai Cancer Institute, Los Angeles, California.

Cancer discovery
|March 3, 2025
PubMed
概括

NOTCH1表达对男性和女性的肝细胞癌 (HCC) 有不同的影响. 在男性中,它有助于抗瘤免疫和免疫治疗反应,而在女性中,它促进HCC发病率和免疫逃逸.

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