一个多学科的德尔菲共识在管理上呼吸道疾病的布德化水性鼻喷雾
Giorgio Ciprandi1, Ignazio La Mantia, Attilio Varricchio
1Casa di Cura Villa Montallegro.
Multidisciplinary respiratory medicine
|March 3, 2025
概括
布德索尼德水性鼻喷雾 (BANS) 有效地管理上呼吸道2型炎症疾病,如过敏性鼻炎. 专家的共识支持其每天用于过敏性鼻炎,非过敏性鼻炎和带鼻息肉的慢性鼻炎.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏学 过敏学
- 儿科 儿科 儿科
背景情况:
- 过敏性鼻炎 (AR),非过敏性鼻炎 (NAR) 和带鼻息肉的慢性鼻炎 (CRSwNP) 分享潜在的2型炎症.
- 鼻内皮质类固醇 (INCS) 是对这些疾病的推治疗方法.
- 布德索尼德水性鼻喷雾 (BANS) 是一个成熟且安全的INCS选择.
研究的目的:
- 建立一个多学科的专家共识,在临床实践中每天使用布松酸水性鼻喷雾 (BANS).
- 评估BANS在管理上呼吸道2型炎症疾病方面的有效性和安全性.
- 根据疾病严重程度为BANS申请提供指导.
主要方法:
- 一个德尔菲共识倡议,涉及46名意大利专家 (耳鼻喉科医生,过敏学家,儿科医生).
- 专家们对21项关于BANS在管理AR,NAR和CRSwNP中的使用的声明进行了投票.
- 协商一致的重点是局部鼻腔治疗的实际应用,疗效和安全性.
主要成果:
- 在所有21个声明上达成了高度一致,支持使用BANS.
- BANS在抑制2型炎症方面表现出显著的活性.
- BANS的安全性概况被认为是有利的,包括生物可用性方面.
结论:
- 共识支持BANS的有价值的使用,用于管理AR,NAR或CRSwNP患者.
- 在上呼吸道疾病中,BANS有效控制2型炎症.
- 治疗的持续时间 (周期或长期) 应根据疾病的严重程度进行调整.
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