老龄化影响基本的审计和时间流程
Antonio Criscuolo1, Michael Schwartze1, Leonardo Bonetti2,3,4
1Department of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
The European journal of neuroscience
|March 3, 2025
概括
老龄化会影响听觉处理,导致语音理解困难. 老年人在处理可预测的声音序列时表现出神经反应的改变和相位对齐的减少,影响基本的时间能力.
科学领域:
- 神经科学是一个神经科学.
- 听觉神经科学 听觉神经科学
- 认知老龄化 认知老龄化
背景情况:
- 与年龄相关的听力和语音理解困难是常见的.
- 老年人的电生理学数据显示神经反应发生变化,以及沿着听觉通路的相位对齐变化.
- 目前尚不清楚与衰老相关的语音处理挑战是否源于基本的听觉和时间缺陷.
研究的目的:
- 研究老年人如何在同时的听觉序列中编码时间规律.
- 检查适应性神经相位对齐机制,以预测衰老中的声音发作.
- 为了确定老年人是否有基本的听觉和时间过程受损.
主要方法:
- 电脑电图 (EEG) 在老年人和年轻人中被记录.
- 参与者听到1.5Hz的简单的同时音序.
- 分析的重点是神经反应,1/F斜率,以及三角形和三角形频段的相连贯性.
主要成果:
- 年长的成年人表现出更大的事件相关的神经反应和增加的1/F斜率.
- 在老年人中观察到刺激频率 (1.5Hz) 的相连贯性降低.
- 随着时间的推移,delta和theta波段的相连贯性倾斜率减少表明神经相位对齐机制发生了变化.
结论:
- 衰老与在处理可预测的听觉序列时改变的上下调节抑制有关.
- 持续神经阶段对应预期的声音发作的机制在衰老中受到损害.
- 老龄化时基本的听觉定时能力的缺陷可能会影响更高阶的认知功能,需要在整个生命周期进行进一步的研究.
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