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Updated: May 24, 2025

Assessing Tumor Microenvironment of Metastasis Doorway-Mediated Vascular Permeability Associated with Cancer Cell Dissemination using Intravital Imaging and Fixed Tissue Analysis
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内皮OX40激活促进瘤细胞通过S1P/YAP介导的血管生成从T细胞监测中逃脱

Baoyu He1, Rou Zhao1, Baogui Zhang2

  • 1Department of Laboratory Medicine.

The Journal of clinical investigation
|March 3, 2025
PubMed
概括

瘤内皮细胞 (ECs) 表达OX40,通过促进血管生成阻碍抗瘤免疫力. 针对这种OX40-SPNS2-S1P-YAP通路可以改善癌症免疫治疗结果.

关键词:
癌症免疫疗法癌症免疫疗法内皮细胞是内皮细胞.免疫学 免疫学 免疫学在瘤学瘤学.

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