艾滋病毒的退行性宫髓病:手术后并发症的发生率和解压手术后的复查率
Henry D Seidel1, Dillon Benson2, Audrey Litvak1
1University of Chicago, Pritzker School of Medicine, Chicago, IL, United States.
North American Spine Society journal
|March 3, 2025
概括
患有人类免疫缺陷病毒 (HIV) 的患者在较年轻时接受了退行性宫髓病 (DCM) 的手术. 虽然艾滋病毒患者有更多的短期医学并发症,但修复和手术并发症率与非艾滋病毒患者相似.
科学领域:
- 神经外科 神经外科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 人类免疫缺陷病毒 (HIV) 与宫骨髓病有关.
- 艾滋病毒对退行性宫肌病 (DCM) 手术的时间和长期结果的影响尚不清楚.
- 在DCM的HIV阳性患者中调查手术时的年龄和术后并发症率至关重要.
研究的目的:
- 确定患有人类免疫缺陷病毒 (HIV) 的患者退行性宫骨髓病 (DCM) 的减压手术的年龄.
- 调查在接受DCM减压的HIV阳性患者中术后并发症和修复手术的发生率.
- 为了比较经过DCM手术的HIV阳性和HIV阴性患者之间的结果.
主要方法:
- 一个国家数据库被用来识别为DCM进行了减压手术的患者.
- 患者根据先前存在的艾滋病毒诊断的存在进行了分层.
- 计算了两年修复手术,手术并发症和90天医疗并发症的两年率,并在各组之间进行了比较.
主要成果:
- 该研究确定了1,014名艾滋病毒阳性患者和153,974名艾滋病毒阴性患者.
- 艾滋病毒阳性患者在减压手术时显著年轻 (53.6岁与57.1岁相比).
- 在两年修订率或植入物移除方面没有发现显著差异. 然而,艾滋病毒患者的2年感染率和神经缺陷较高,以及肺炎,尿道感染和功能衰竭等90天的医疗并发症增加.
结论:
- 艾滋病毒感染患者在较年轻时接受DCM的减压手术,尽管这种差异的临床意义尚不确定.
- 尽管短期医学并发症率较高,但艾滋病毒阳性患者没有经历2年修复手术或需要重新手术的手术并发症的增加率.
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