对动脉硬性性别特异性风险因素的分析
Jinhuan Yuan1, Chengwen Wang2, Chong Zhao1
1Zhifu Center for Disease Control and Prevention, 264000 Yantai, Shandong, China.
Reviews in cardiovascular medicine
|March 3, 2025
概括
男性的动脉硬化发病率较高,但45岁以上的女性的动脉硬性增加得更快. 糖尿病和LDL-C等危险因素与女性的动脉样硬化更为密切相关.
科学领域:
- 心血管健康 心血管健康
- 流行病学 流行病学
- 性别特异性医学是指性别特异性医学.
背景情况:
- 动脉硬是心血管事件的预测因素,在性别之间可能有不同的危险因素.
- 了解这些性别特异性因素对于有针对性的预防策略至关重要.
研究的目的:
- 调查与动脉硬相关的性别特异性风险因素.
- 为了分析男性和女性之间的动脉样硬化 (通过脚脉冲波速度测量,baPWV) 的差异.
主要方法:
- 利用了Kailuan研究队列中的28291名参与者的数据.
- 采用多变量线性和逻辑回归模型来识别baPWV的影响因素,按性别分层.
主要成果:
- 动脉样硬化发生率在男性 (62.13%) 比女性 (37.41%) 高.
- 虽然男性在年轻年龄组的baPWV较高,但在45岁以上的女性中,baPWV的增加速度更快.
- 腰与部比率,糖尿病,LDL-C和hs-CRP等因素与女性的动脉样硬化更强烈相关.
结论:
- 男人表现出更高的整体检测率的动脉样硬化.
- 在45岁后的女性中,动脉硬度的进展更为明显,糖尿病,LDL-C和hs-CRP等特定危险因素的影响更大.
- 高等教育与男性和女性的动脉样硬化风险降低有关.
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