在食道切除术后患有食道癌的患者中,术后肺炎的预测模型
Jing Chen1, Qian Xiang1, Xiao-Jia Zheng1
1Department of Healthcare-associated Infection Control Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Frontiers in oncology
|March 3, 2025
概括
这项研究确定了食道癌患者手术后肺炎 (POP) 的关键风险因素. 使用机械通风和输血的预测模型可以帮助临床医生减少POP发生率.
科学领域:
- 在瘤学瘤学.
- 胸部外科手术 胸部外科手术
- 关键护理医学 关键护理医学
背景情况:
- 手术后的肺炎 (POP) 是食道切除术后的常见并发症.
- 在食道癌患者中,POP显著影响食道癌患者的生存率.
- 识别风险因素和预测POP对于患者管理至关重要.
研究的目的:
- 在食道癌患者中确定术后肺炎 (POP) 的独立风险因素.
- 开发和验证用于POP风险评估的预测模型 (nomogram).
主要方法:
- 对667名经过食道切除术的食道癌患者进行了回顾性队列研究.
- 对于因子选的最小绝对收缩和选择操作员 (LASSO) 回归.
- 使用AUC,校准曲线和DCA进行诺摩图构造和性能评估.
主要成果:
- 61名患者 (9.1%) 患有POP.
- 独立的POP预测因素:机械通风>2天和输血.
- 预测模型表现出强大的区分能力 (AUC=0.839) 和良好的预测值.
结论:
- 一个经过验证的诺姆图可以预测食道癌症患者的POP风险.
- 早期识别高风险患者有助于及时进行临床干预.
- 该模型旨在减少手术后肺炎的发生率.
相关概念视频
Pneumonia V: Nursing management and Prevention
1.8K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
1.8K
Pneumonia I: Introduction
201
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
201
Pneumonia IV: Management
286
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
286
Pneumonia III: Complications and Assessment
140
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
140
Pneumothorax-II
112
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
112
Esophageal Perforation-II: Clinical Manifestations and Management
31
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
31


