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全球TFH细胞和瘤的研究前景和趋势:一个文献计量分析

Hao Lei¹, Jin Hu², Junpeng Zhu³

¹Department of Breast and Thyroid Surgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.

Frontiers in oncology

|March 3, 2025

概括

毛囊T辅助细胞 (TFH) 对于抗体反应至关重要,并与癌症有关. 本文献分析揭示了瘤微环境中的TFH细胞日益关注的研究重点,突出了它们的免疫治疗潜力.

科学领域:

免疫学免疫学免疫学
在瘤学瘤学.
图书统计学图书统计学

背景情况:

毛囊T辅助细胞 (TFH) 是关键的CD4+T细胞子集,对B细胞激活和抗体产生至关重要.
TFH细胞与各种疾病有关,包括自身免疫性疾病,感染,过敏和癌症.
缺乏专门针对瘤的TFH细胞的综合性审查.

研究的目的:

对全球关于T毛囊辅助细胞 (TFH) 和瘤的研究环境进行文献计量分析.
确定该领域的研究趋势,热点和合作.
提供有关未来TFH细胞研究在瘤学的方向的见解.

主要方法:

2012-2024年使用Web of Science核心集合对文献进行图书法分析.
使用VOSviewer,CiteSpace和R语言进行数据分析.
包括系统审查来总结研究趋势和前景.

主要成果:

在过去的十年中,对TFH细胞和瘤的研究稳步增加,中国的出版物领先.
来自高拉德,菲利普和德勒瓦尔,劳伦斯等作家和主要在中国的机构的重大贡献.
领先的期刊包括免疫学和免疫力的边界.
研究重点显著转向瘤微环境和免疫透.

结论:

TFH细胞具有显著的研究价值和瘤免疫治疗中临床应用的潜力.
这种文献计量分析可以作为未来该领域研究的宝贵参考.
进一步的基础和临床研究对于进一步了解和应用TFH细胞在瘤学中至关重要.

关键词:

在CD4+Th细胞中.细胞Tfh细胞Tfh细胞文献计量数据库 (bibliometrics) 是一个免疫系统是免疫系统的.瘤是一个瘤.

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