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Updated: May 24, 2025

Studies of Chaperone-Cochaperone Interactions using Homogenous Bead-Based Assay
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Published on: July 21, 2021

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酸化状态调节的HSP70结合:结构见解和补偿蛋白质工程

Mariah Stewart1,2, Chathura Paththamperuma3, Colleen McCann1

  • 1The McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

bioRxiv : the preprint server for biology
|March 3, 2025
PubMed
概括

热冲击蛋白70 (HSP70) 在T636的酸化削弱了它与E3酶CHIP的相互作用,影响了蛋白质质量控制. 这一发现为与蛋白质稳定失衡相关的疾病提供了洞察力.

关键词:
芯片 (HSC70相互作用蛋白的C端)陪伴者是指一个陪伴者.一个共同的主管.在HSP70中,HSP70是酸化是指酸化的方法.后翻译修改后的修改.蛋白质质量控制 蛋白质质量控制

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